To install particular Ensembl human release(s):

pyensembl install --release 75 77

To install particular Ensembl mouse release(s):

pyensembl install --release 75 77 --species mouse

To delete all downloaded and cached data for a particular Ensembl release:

pyensembl delete-all-files --release 75 --species human

To delete only cached data related to transcript and protein sequences:

pyensembl delete-index-files --release 75

To list all installed genomes:

pyensembl list

To install a genome from source files:

pyensembl install

--reference-name "GRCh38" --gtf URL_OR_PATH --transcript-fasta URL_OR_PATH --protein-fasta URL_OR_PATH

pyensembl: error: the following arguments are required: action